
Professor in Residence
M_Neurology
Josh Berke's laboratory at UCSF investigates brain mechanisms involved in learning, motivation and decision-making, and how these mechanisms go awry in disorders such as drug addiction, Parkinson's Disease and Huntington's Disease. (see www.berkelab.org). He is also Director of the Alcohol and Addiction Research Group, and holds the Rudi Schmid Distinguished Professorship in Neurology.
Publications
Reward expectation and receipt differentially modulate the spiking of accumbens D1+ and D2+ neurons.
Current biology : CB
A mismatch between striatal cholinergic pauses and dopaminergic reward prediction errors.
Proceedings of the National Academy of Sciences of the United States of America
Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands.
bioRxiv : the preprint server for biology
Dopamine transients follow a striatal gradient of reward time horizons.
Nature neuroscience
Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'.
bioRxiv : the preprint server for biology
Selective encoding of reward predictions and prediction errors by globus pallidus subpopulations.
Current biology : CB
Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation.
eLife
Dual credit assignment processes underlie dopamine signals in a complex spatial environment.
bioRxiv : the preprint server for biology
Coupling between motor cortex and striatum increases during sleep over long-term skill learning.
eLife
Improved inference in coupling, encoding, and decoding models and its consequence for neuroscientific interpretation.
Journal of neuroscience methods
High density carbon fiber arrays for chronic electrophysiology, fast scan cyclic voltammetry, and correlative anatomy.
Journal of neural engineering
Cellular-scale silicon probes for high-density, precisely localized neurophysiology.
Journal of neurophysiology
The Degree of Nesting between Spindles and Slow Oscillations Modulates Neural Synchrony.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Dopamine release drives motivation, independently from dopamine cell firing.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
What does dopamine mean?
Nature neuroscience
Sensorimotor Processing in the Basal Ganglia Leads to Transient Beta Oscillations during Behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience
(Invited) Carbon Fiber Electrode Array for the Detection of Electrophysiological and Dopaminergic Activity.
ECS Meeting Abstracts
A Pause-then-Cancel model of stopping: evidence from basal ganglia neurophysiology.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Acetylcholine Release in Prefrontal Cortex Promotes Gamma Oscillations and Theta-Gamma Coupling during Cue Detection.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Cell Assembly Dynamics of Sparsely-Connected Inhibitory Networks: A Simple Model for the Collective Activity of Striatal Projection Neurons.
PLoS computational biology
Cortical cholinergic signaling controls the detection of cues.
Proceedings of the National Academy of Sciences of the United States of America
Cell assembly dynamics of sparse inhibitory networks: a simple model for the activity of the Medium Spiny Neurons.
BMC Neuroscience
Mesolimbic dopamine signals the value of work.
Nature neuroscience
Silk-Backed Structural Optimization of High-Density Flexible Intracortical Neural Probes.
Journal of Microelectromechanical Systems
Silk-backed structural optimization of high-density flexible intracortical neural probes
IEEE Journal on Microelectromechanical Systems
New roles for the external globus pallidus in basal ganglia circuits and behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Dissociable effects of dopamine on learning and performance within sensorimotor striatum.
Basal ganglia
Control of basal ganglia output by direct and indirect pathway projection neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Canceling actions involves a race between basal ganglia pathways.
Nature neuroscience
Selective inhibition of striatal fast-spiking interneurons causes dyskinesias.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Striatal fast-spiking interneurons: from firing patterns to postsynaptic impact.
Frontiers in systems neuroscience
Functional properties of striatal fast-spiking interneurons.
Frontiers in systems neuroscience
Integrating early results on ventral striatal gamma oscillations in the rat.
Frontiers in neuroscience
Memory formation: from network structure to neural dynamics.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Local dynamics of gap-junction-coupled interneuron networks.
Physical biology
Opposite effects of stimulant and antipsychotic drugs on striatal fast-spiking interneurons.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Corticostriatal Interactions during Learning, Memory Processing, and Decision Making.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Striatal interneurons and reward prediction errors (Commentary on Apicella et al.).
The European journal of neuroscience
Fast oscillations in cortical-striatal networks switch frequency following rewarding events and stimulant drugs.
The European journal of neuroscience
Functional clustering algorithm for the analysis of dynamic network data.
Physical review. E, Statistical, nonlinear, and soft matter physics
Striatal versus hippocampal representations during win-stay maze performance.
Journal of neurophysiology
Procedural Learning: Striatum.
Encyclopedia of Neuroscience
Uncoordinated firing rate changes of striatal fast-spiking interneurons during behavioral task performance.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Functional structure from dynamic clustering of spike train data.
BMC Neuroscience
Wavelet filtering before spike detection preserves waveform shape and enhances single-unit discrimination.
Journal of neuroscience methods
Transient 23-30 Hz oscillations in mouse hippocampus during exploration of novel environments.
Hippocampus
The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump.
Biochemical and biophysical research communications
Participation of Striatal Neurons in Large-Scale Oscillatory Networks.
The Basal Ganglia VIII
Analysis of mRNA expression in striatal tissue by differential display polymerase chain reaction.
Methods in molecular medicine
Learning and memory mechanisms involved in compulsive drug use and relapse.
Methods in molecular medicine
Drug addiction and the hippocampus.
Science (New York, N.Y.)
A complex program of striatal gene expression induced by dopaminergic stimulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Affiliation