
Professor and Chief
Medicine
+1 415 476-9623
Dr. Suneil Koliwad is an Expert in Diabetes, Obesity, and Metabolism, serving as Chief of the Division of Endocrinology and Metabolism at UCSF Health. His lab, based in the UCSF Diabetes Center, focuses on the intersection of nutrition, inflammation, and metabolic tissue function in the context of normal physiology, and diseases such as obesity, diabetes, fatty liver disease, and in the course of aging. His group strives to link basic mechanisms of metabolic regulation to causality in important clinical contexts, and has developed a highly innovative and deeply curated multiethnic obesity cohort at UCSF to assist in achieving this goal.
Publications
Consensus on the key characteristics of metabolism disruptors.
Nature reviews. Endocrinology
The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors.
Journal of diabetes science and technology
8154 The Pro-Fibrotic Transcriptional Profile of Adipose Tissue in Insulin Resistant Individuals.
Journal of the Endocrine Society
Microglia mediate the early-life programming of adult glucose control.
bioRxiv : the preprint server for biology
Novel Automated Self-adjusting Subcutaneous Insulin Algorithm Improves Glycemic Control and Physician Efficiency in Hospitalized Patients.
Journal of diabetes science and technology
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
The Journal of biological chemistry
Second-Line Pharmaceutical Treatments for Patients with Type 2 Diabetes.
JAMA network open
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance.
Cell metabolism
Twenty-first century management of diabetes with shared telemedicine appointments.
Journal of telemedicine and telecare
MFGE8 inhibits insulin signaling through PTP1B.
bioRxiv : the preprint server for biology
Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop.
The American journal of clinical nutrition
407 Moving from observational studies to a clinical trial: the impact of obesity and surgical weight loss on breast imaging, tissue, and cancer screening experience: the B-BRITE study.
Journal of Clinical and Translational Science
The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.
American journal of respiratory and critical care medicine
Excess natural-cause deaths in California by cause and setting: March 2020 through February 2021.
PNAS nexus
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis.
Science signaling
Metabolic factors in the regulation of hypothalamic innate immune responses in obesity.
Experimental & molecular medicine
A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings.
Journal of diabetes science and technology
A gene-diet interaction controlling relative intake of dietary carbohydrates and fats.
Molecular metabolism
Reducing Methylglyoxal Rescues Obesity Related Phenotypes and Lifespan in a Leptin Receptor Deficient Mouse Model.
Innovation in Aging
Reducing Methylglyoxal Rescues Obesity Related Phenotypes and Lifespan in a Leptin Receptor Deficient Mouse Model.
Innovation in Aging
The relationship between physical activity intensity and volume on prospective falls in older adults.
Innovation in Aging
Probing Insulin Sensitivity with Metabolically Competent Human Stem Cell-Derived White Adipose Tissue Microphysiological Systems.
Small (Weinheim an der Bergstrasse, Germany)
Continuous Ketone Monitoring Consensus Report 2021.
Journal of diabetes science and technology
Microglial Lipid Biology in the Hypothalamic Regulation of Metabolic Homeostasis.
Frontiers in endocrinology
Invariant Natural Killer T cells coordinate removal of senescent cells.
Med (New York, N.Y.)
Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin.
Proceedings of the National Academy of Sciences of the United States of America
Lack of association between either outpatient or inpatient glycemic control and COVID-19 illness severity or mortality in patients with diabetes.
BMJ open diabetes research & care
Continuous Ketone Monitoring: A New Paradigm for Physiologic Monitoring.
Journal of diabetes science and technology
Quantifying Variation in Treatment Utilization for Type 2 Diabetes Across Five Major University of California Health Systems.
Diabetes care
Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice.
British journal of anaesthesia
Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking.
American journal of physiology. Endocrinology and metabolism
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.
Nature microbiology
Obesity and Fat Metabolism in Human Immunodeficiency Virus-Infected Individuals: Immunopathogenic Mechanisms and Clinical Implications.
The Journal of infectious diseases
mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes.
The Journal of clinical investigation
Sweet cognition: The differential effects of glucose consumption on attentional food bias in individuals of lean and obese status.
Physiology & behavior
Hypothalamic microglia as potential regulators of metabolic physiology.
Nature metabolism
Fighting obesity by targeting factors regulating beige adipocytes.
Current opinion in clinical nutrition and metabolic care
Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans.
The Journal of clinical endocrinology and metabolism
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility.
Cell metabolism
Regulation of Hepatic Lipid Accumulation and Distribution by Agouti-Related Protein in Male Mice.
Endocrinology
Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice.
British journal of anaesthesia
Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.
Cell metabolism
Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes.
The Journal of biological chemistry
The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure.
The Journal of biological chemistry
Digital Diabetes Congress 2017.
Journal of diabetes science and technology
Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis.
Cell metabolism
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility.
Cell metabolism
Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier.
Cell reports
GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance.
JCI insight
The Electronic CardioMetabolic Program (eCMP) for Patients With Cardiometabolic Risk: A Randomized Controlled Trial.
Journal of medical Internet research
Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
Cell reports
Leptin potentiates astrogenesis in the developing hypothalamus.
Molecular metabolism
Hypothalamic inflammation in the control of metabolic function.
Annual review of physiology
Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.
Cell reports
A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
Hepatology (Baltimore, Md.)
Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.
Journal of Biological Chemistry
Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytes.
The Journal of biological chemistry
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.
Journal of Clinical Investigation
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.
The Journal of clinical investigation
Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.
The Journal of biological chemistry
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis.
Journal of lipid research
Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin.
American journal of physiology. Endocrinology and metabolism
Increased longevity in mice lacking DGAT1.
The FASEB Journal
4 Redox Regulation of Ion Channels.
Antioxidant and Redox Regulation of Genes
Analysis of a Ca2+-activated K+ channel that mediates hyperpolarization via the thrombin receptor pathway.
The American journal of physiology
Redox control of ion channel activity in vascular endothelial cells by glutathione.
Microcirculation (New York, N.Y. : 1994)
Oxidized glutathione mediates cation channel activation in calf vascular endothelial cells during oxidant stress.
The Journal of physiology
Oxidant stress activates a non-selective cation channel responsible for membrane depolarization in calf vascular endothelial cells.
The Journal of physiology
Oxidant stress and endothelial membrane transport.
Free radical biology & medicine
Affiliation