Professor
M_PEDS-CRITICAL CARE
Publications
Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium.
bioRxiv : the preprint server for biology
Loss of TRPV4 decreases NFκB-mediated myometrial inflammation and prevents preterm labor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
miR-203 modulates pregnant myometrium contractility via transient receptor potential vanilloid 4 channel expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Pediatric subspecialty workforce: what is needed to secure its vitality and survival?
Pediatric research
Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report.
American journal of respiratory cell and molecular biology
Seeing pulmonary hypertension through a paediatric lens: a viewpoint.
The European respiratory journal
Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity.
Scientific reports
Integrative analysis of noncoding mutations identifies the druggable genome in preterm birth.
Science advances
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.
Inflammation and regeneration
Loss of prolyl hydroxylase 1 and 2 in SM22α-expressing cells prevents Hypoxia-Induced pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
Hypoxia-Inducible Factor-1α in SM22α-Expressing Cells Modulates Alveolarization.
American journal of respiratory cell and molecular biology
Endothelial-specific loss of IKKβ disrupts pulmonary endothelial angiogenesis and impairs postnatal lung growth.
American journal of physiology. Lung cellular and molecular physiology
Wnt7a deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension.
The European respiratory journal
SM22α cell-specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury.
American journal of physiology. Lung cellular and molecular physiology
Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia.
The European respiratory journal
Dynamism of the Human Lung Proteome during Alveolarization: Moving beyond the Transcriptome.
American journal of respiratory and critical care medicine
Transforming Growth Factor-induced Protein Promotes NF-κB-mediated Angiogenesis during Postnatal Lung Development.
American journal of respiratory cell and molecular biology
Nanoparticle Delivery of Angiogenic Gene Therapy. Save the Vessels, Save the Lung!
American journal of respiratory and critical care medicine
NF-κB/NKILA signaling modulates the anti-cancerous effects of EZH2 inhibition.
Journal of cellular and molecular medicine
Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success.
The Journal of pediatrics
Distinct roles for IκB kinases alpha and beta in regulating pulmonary endothelial angiogenic function during late lung development.
Journal of cellular and molecular medicine
Pulmonary artery smooth muscle cell HIF-1α regulates endothelin expression via microRNA-543.
American journal of physiology. Lung cellular and molecular physiology
Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep.
American journal of physiology. Lung cellular and molecular physiology
β1-Subunit of the calcium-sensitive potassium channel modulates the pulmonary vascular smooth muscle cell response to hypoxia.
American journal of physiology. Lung cellular and molecular physiology
Developmental differences in focal adhesion kinase expression modulate pulmonary endothelial barrier function in response to inflammation.
American journal of physiology. Lung cellular and molecular physiology
Can We Understand the Pathobiology of Bronchopulmonary Dysplasia?
The Journal of pediatrics
Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model.
Physiological reports
Aberrant Pulmonary Vascular Growth and Remodeling in Bronchopulmonary Dysplasia.
Frontiers in medicine
Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation.
American journal of physiology. Lung cellular and molecular physiology
Loss of PPARγ in endothelial cells leads to impaired angiogenesis.
Journal of cell science
The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy.
Science translational medicine
Activation of the nuclear factor-κB pathway during postnatal lung inflammation preserves alveolarization by suppressing macrophage inflammatory protein-2.
American journal of physiology. Lung cellular and molecular physiology
Pulmonary artery smooth muscle cell endothelin-1 expression modulates the pulmonary vascular response to chronic hypoxia.
American journal of physiology. Lung cellular and molecular physiology
Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome.
Arteriosclerosis, thrombosis, and vascular biology
Haemophagocytic lymphohistiocytosis associated with coccidiomycosis.
BMJ case reports
Disrupted lung development and bronchopulmonary dysplasia: opportunities for lung repair and regeneration.
Current opinion in pediatrics
Nuclear factor-kappa-B signaling in lung development and disease: one pathway, numerous functions.
Birth defects research. Part A, Clinical and molecular teratology
Chronic lung disease in the preterm infant. Lessons learned from animal models.
American journal of respiratory cell and molecular biology
Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation.
Circulation research
Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production.
American journal of respiratory cell and molecular biology
Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization.
American journal of physiology. Lung cellular and molecular physiology
Hypoxia-inducible factor-1α regulates KCNMB1 expression in human pulmonary artery smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology
miR-29b participates in early aneurysm development in Marfan syndrome.
Circulation research
Neutrophil elastase is produced by pulmonary artery smooth muscle cells and is linked to neointimal lesions.
The American journal of pathology
Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease.
The American journal of pathology
Rho kinase modulates postnatal adaptation of the pulmonary circulation through separate effects on pulmonary artery endothelial and smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology
Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice.
American journal of physiology. Lung cellular and molecular physiology
Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.
American journal of physiology. Lung cellular and molecular physiology
LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor.
Journal of cell science
An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension.
The Journal of clinical investigation
Reactivation of gammaHV68 induces neointimal lesions in pulmonary arteries of S100A4/Mts1-overexpressing mice in association with degradation of elastin.
American journal of physiology. Lung cellular and molecular physiology
Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice. Prelude to defective alveolar septation during lung development?
American journal of physiology. Lung cellular and molecular physiology
Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation.
American journal of respiratory and critical care medicine
Affiliation